Botox, Collagen and Lipo-Therapy without the needle!     

      
Transderm® Meso® System® is a new needle free injection system for trans-dermal drug delivery. Transderm® Meso® System® makes the skin permeable to macromolecules (up to a million dalton – Biopsy available), in a non-invasive way.
Transderm® delivers active substances without trauma, skin injury and irritations.
Transderm® is an alternative to injections for all Mesotherapy applications, mainly skin rejuvenation on face, neck, chest and hands and cellulite treatments That's why the American FDA cleared the system as: "Can be used as alternative to injections".

• Transderm replaces the often hundreds of painful injections during Mesotherapy applications.

• Even under-arm Botox® treatments for excessive sweating can be done without the need for injections

• Collagen and Growth Factors: Application of high purity Hyaluronic Acid for its antioxidant and hydrating properties combined with TGF beta synthesized by epitelial growth factors, which increases collagen synthesis and inhibits the extra cellular matrix degradation (skin ageing) for face, neck and chest.

Dermoelectroporation® allows the absorption of large molecular size drugs (even with a molecular weight such as Hyaluronic Acid 1,700.000dalton) into the skin in about 10 to 20 minutes, depending on the area and the individual patient's skin. The procedure temporarily lowers the patient’s skin impedance and allows for transdermal drug delivery in a homogeneous way over the whole treatment area.
Transderm® does not cause any bruising or downtime, a common side effect linked to conventional meso-therapy.
Transderm® can be used to deliver drugs, growth factors, active ingredients, collagen and vitamins into the skin without causing physical damage to the skin and in a very controlled and precise manner.

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  Transderm® can be applied on the face, neck and chest where collagen and elastin, antioxidants, growth factors and Botox® is usually injected. The substances used for anti-ageing and skin rejuvenation are: Hyaluronic Acid, Amino Acids, Collagen, Elastine, Glutathione, MTE-4 (Copper Manganese-Zinc Sulphate-Chromium), Lidocaine, growth factors.

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  Transderm can also be used on larger areas such as thighs, stomach and buttocks for cellulite reduction and the treatment of stubborn fat deposits, these areas would require hundreds of injections with conventional mesotherapy. The active fat-burning substances are: Phosphatidylcoline, Aminophylline, L-Carnitine, Vitamins.

 How does Transderm work?

Prior to Transderm® a superficial microdermbarsion is carried out in order to reduce skin resistance and increase the permeability of the skin.

Step1 - Microdermabrasion

Ultrapeel® Microdermabrasion is controlled exfoliation of the stratum corneum through a pre-sterilized jet of corundum crystals. The controlled abrasion and the sterility of the treatment causes virtually no irritation to the skin and no change in skin PH. The microdermabrasion standardizes the skin characteristics for reproducible drug delivery rate.

Step 2 – Transdermal Delivery

Ultrapeel® Transderm® Meso® System works as a pulsed Ionthophoresis (low currents from 1 to 5 mA as the medical devices rules require) The Ultrapeel®Transderm® Meso System uses particular electrical pulses synchronized with a vibration massage that increases the skin permeability to allow the drug delivery. The active substances are applied on the skin where gentle massage with the Transderm® meso-system facilitates easy penetration and absorption of the active substances into the dermis. The whole procedure takes about 45min and is very enjoyable.

Advantages

The advantages in using the Ultrapeel®Transderm® Meso System compared to conventional injection therapy are:

No trauma, bruising, lesions or skin irritations
The procedure is virtually painless
Very even drug distribution of very small amounts possible

For more information: http://www.mattioliengineering.eu/index.html